Transperineal Biopsy of the Prostate

What is transperineal biopsy of the prostate?

Transperineal biopsy of the prostate is a method of sampling the prostate to establish a diagnosis of prostate cancer. Under a general anaesthetic, an ultrasound probe is passed into the rectum or back passage to visualise the prostate, and using fine biopsy needles multiple samples are taken through the perineum, which is the section of skin between the anus and scrotum. The alternative method is called TRUS biopsy in which the samples are taken through the rectal wall.

What are the advantages of transperineal biopsy?

The infection rate is lower with this method of biopsy and is reportedly 1 in 400 cases. This method of biopsy should be considered complimentary to TRUS biopsy of the prostate but occasionally there are instances where the TRUS approach may be preferred in some patients for technical reasons.

What are the disadvantages of transperineal biopsy?

The disadvantages of transperineal biopsy include a higher rate of urinary retention or inability to pass urine compared to TRUS biopsy, which is reported to occur in 1-2% of cases.

What is my expected recovery after a transperineal biopsy?

Most patients have some soreness and occasional bruising after this biopsy, which is more significant than with TRUS biopsy. This bruising will resolve as the body heals after a few weeks. Some blood in the urine, bowel motions and semen is normal for the first 6 weeks after the biopsy.

When do I get my biopsy results?

The pathology results are usually available within 1 week after a biopsy. Your urologist will discuss these results with you at an appointment in the consulting rooms. Antibiotics are not usually prescribed after this form of biopsy.

  • Royal Australasian College of Surgeons (RACS)
  • Sydney Adventist Hospital
  • American Urological Association (AUA)
  • Australian Medical Association (AMA)
  • Norwest Private Hospital
  • The University of Sydney
  • European Association of Urology (EAU)